Journal article
ACTN3 and ACE genotypes in elite Jamaican and US sprinters
RA Scott, R Irving, L Irwin, E Morrison, V Charlton, K Austin, D Tladi, M Deason, SA Headley, FW Kolkhorst, N Yang, K North, YP Pitsiladis
Medicine and Science in Sports and Exercise | LIPPINCOTT WILLIAMS & WILKINS | Published : 2010
Abstract
The angiotensin-converting enzyme (ACE) and the α-actinin-3 (ACTN3) genes are two of the most studied "performance genes" and both have been associated with sprint/power phenotypes and elite performance. PURPOSE: To investigate the association between the ACE and the ACTN3 genotypes and sprint athlete status in elite Jamaican and US African American sprinters. METHODS: The ACTN3 R577X and the ACE I/D and A22982G (rs4363) genotype distributions of elite Jamaican (J-A; N = 116) and US sprinters (US-A; N = 114) were compared with controls from the Jamaican (J-C; N = 311) and US African American (US-C; N = 191) populations. Frequency differences between groups were assessed by exact test. RESULT..
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Funding Acknowledgements
This study was part funded by internal funds from the University of Glasgow.