Calpain cleavage within dysferlin exon 40a releases a synaptotagmin-like module for membrane repair

Grants

Funding Acknowledgements

We gratefully acknowledge Jianjie Ma and Noah Weisleder (University of Medicine and Dentistry of New Jersey, Piscataway, NJ) for the polyclonal anti-MG53 antibody. We thank the Children's Medical Research Institute Flow Cytometry Facility for their technical assistance and Laurence Cantrill for technical assistance with confocal microscopy. We thank the funding bodies supporting our work: the Australian National Health and Medical Research Council (Project Grant APP1048814 to S.T.C. and K.M.; Career Development Fellowship APP1048816 to S.T.C.; and Ph.D. Scholarship to F.L.), the Jain Foundation (S.T.C.), the University of Sydney for postgraduate awards (G.R., N.W., and A.K.P.), the Brain Foundation (S.T.C. and K.N.), and the Canadian Institutes of Health Research (P.A.G.). The Leica SP5 in the Correlative Light and Electron Microscope Suite at Kids Research Institute, Children's Hospital at Westmead, was supported by the Cancer Institute New South Wales (Research Equipment 10/REG/1-23), the Australian National Health and Medical Research Council (2009-02759), the Ian Potter Foundation (20100508), the Perpetual Foundation (730), the Ramaciotti Foundation (3037/2010), and the Sydney Medical School Research Infrastructure Major Equipment Scheme.