Journal article

Cognitive reserve in bipolar disorder: relation to cognition, psychosocial functioning and quality of life

C Anaya, C Torrent, FF Caballero, E Vieta, C del Mar Bonnin, JL Ayuso-Mateos

Acta Psychiatrica Scandinavica | WILEY | Published : 2016

Abstract

OBJECTIVE: Cognitive reserve (CR) is a concept that was postulated as a protective factor for some clinical symptoms after the observation that there is not a direct relationship between the degree of brain damage and its clinical manifestation. This study aimed to explore the association between CR and the main outcomes in bipolar disorder (BD): cognitive functions, psychosocial functioning and perceived quality of life. METHOD: A sample of 224 euthymic bipolar patients was assessed with a neuropsychological battery, the Functioning Assessment Short Test and the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). CR was calculated through three proxies: estimated premorbid Inte..

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University of Melbourne Researchers

Grants

Awarded by Spain's Ministries of the Economy and Competitiveness and of Education, Culture and Sport


Awarded by Centro de Investigacion Biomedica en Red de Salud Mental (CIBERSAM)


Awarded by Instituto de Salud Carlos III


Awarded by Comissionat per a Universitats i Recerca del DIUE of the Generalitat de Catalunya


Awarded by Instituto Carlos III, through a 'Miguel Servet' postdoctoral contract


Awarded by FIS


Funding Acknowledgements

The authors of this study would like to acknowledge the support to the Bipolar Disorders Group (2014 SGR 398) of Spain's Ministries of the Economy and Competitiveness and of Education, Culture and Sport; Centro de Investigacion Biomedica en Red de Salud Mental (CIBERSAM); Instituto de Salud Carlos III; and the Comissionat per a Universitats i Recerca del DIUE of the Generalitat de Catalunya. Celia Anaya was funded by the FPU programme (Formacion de Profesorado Universitario) of the Ministry of Education of Spain. Dr. Carla Torrent is funded by the Spanish Ministry of Economy and Competitiveness and by Instituto Carlos III, through a 'Miguel Servet' postdoctoral contract (CP14/00175) and a FIS (PI 12/01498). Dr. Torrent's project is also supported in part by a 2014 NARSAD, Independent Investigator Grant from the Brain & Behavior Research Foundation.