Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group
Yi Su, Tyler M Blazey, Christopher J Owen, Jon J Christensen, Karl Friedrichsen, Nelly Joseph-Mathurin, Qing Wang, Russ C Hornbeck, Beau M Ances, Abraham Z Snyder, Lisa A Cash, Robert A Koeppe, William E Klunk, Douglas Galasko, Adam M Brickman, Eric McDade, John M Ringman, Paul M Thompson, Andrew J Saykin, Bernardino Ghetti Show all
PLOS ONE | PUBLIC LIBRARY SCIENCE | Published : 2016
Awarded by National Institute of Health
Awarded by National Institute of Neurological Disorders and Stroke
Awarded by National Institute of Ageing
Awarded by National Institute for Health Research
YS received funds from the Knight Alzheimer's Disease Research Center (http://knightadrc.wustl.edu/) pilot award, Washington University Institute of Clinical and Translational Sciences (http://icts.wustl.edu/) Pilot Grant supported by the Clinical and Translational Science Award (CTSA) program (https://www.ctsacentral.org/) of National Institute of Health (http://www.nih.gov/): UL1TR000448. AZS and DSM received funds from National Institute of Neurological Disorders and Stroke (http://www.ninds.nih.gov/): P30NS048056; JCM and TLSB received funds from National Institute of Ageing (http://www.nia.nih.gov/): P01AG026276, U19AG032438, P50AG005681, P01AG003991. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.We acknowledge the altruism of the DIAN participants and their families and contributions of the DIAN research. We acknowledge the DIAN genetics core for APOE genotype and mutation status; the DIAN clinical core for providing CDR status; and the DIAN biostatistics, informatics, neuropathology, and biomarker cores for their assistance in the DIAN project. We acknowledge each of the participating sites (list follows in alphabetical order) and their staff for their contributions to this study (see DIAN website (www.DIAN-info.org) for a list of DIAN sites and other DIAN related information). We also acknowledge Alzheimer's Disease Cooperative Study (ADCS) for coordination of clinical and neuropsychological evaluations and monitoring of the acquisition of imaging studies and collection of biological fluids; Mayo Clinic Rochester for MRI site training and standardization; University of Michigan for PET site training and standardization; and San Francisco Veteran's Administration Medical Center and Alzheimer's Disease Neuroimaging Initiative (ADNI) for the assistance in the conduct of project research. Support was also provided by the NIHR Queen Square Dementia Biomedical Research Unit.