Journal article

Predictors of depression and anxiety symptom trajectories in the 24 months following diagnosis of breast or gynaecologic cancer

Lesley Stafford, Angela Komiti, Chad Bousman, Fiona Judd, Penny Gibson, G Bruce Mann, Michael Quinn



OBJECTIVE: To identify predictors of anxiety and depression symptom trajectories, as distinct from general distress, in the 96 weeks following diagnosis of breast or gynaecologic cancer. METHODS: Participants completed the Hospital Anxiety and Depression Scale anxiety subscale (HADS-A) and Centre for Epidemiological Studies Depression Scale (CES-D) at diagnosis and at 8-weekly intervals for 96 weeks. Linear mixed models were used to determine the effects of age, relationship status, tumour stream, cancer stage, living situation, residential area, educational status, current and previous anxiety/depression treatment and neuroticism on symptom trajectories. RESULTS: Participants were 264 women..

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Funding Acknowledgements

This study was supported in part by funding from the Western and Central Melbourne Integrated Cancer Service (WCMICS). The Centre for Women's Mental Health is supported by the Pratt Foundation. The funding sources had no role in the study design, or collection, analysis and interpretation of data; or in the decision to submit the work for publication. The authors wish to thank the Breast Care Nurses Robyn Cordner, Monique Baldacchino, Kerry Shanahan, Bronwyn Flanagan and Claire Noonan for their assistance in recruiting patients to the study. We also thank the participating patients for their support of this research.