Journal article

Crotaleschenine, an alkaloid of Crotalaria leschenaultii

LW Smith, JA Edgar, RI Willing, RW Gable, MF Mackay, OP Suri, CK Atal, CCJ Culvenor

Australian Journal of Chemistry | CSIRO PUBLISHING | Published : 1988

Abstract

An alkaloid of Crotalaria leschenaultii DC., previously reported as crispatine and now named crotaleschenine, has been re-investigated and shown to be (7ß, 8a-H, 12a, 13a, 14a)-12ß-hydroxy- 1, 2-didehydrocrotalane-11, 15-dione.1 Spectroscopic data are presented and the stereochemistry determined by X-ray crystallography. The esterifying acid of crotaleschenine is identical with that of retusine, which is thereby determined as (1a, 7ß, 8a-H, 12a, 13a, 14a)-12ß-hydroxycrotalane-11, 15-dione. © 1988 ASEG.

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