Latitude, sun exposure and vitamin D supplementation: associations with quality of life and disease outcomes in a large international cohort of people with multiple sclerosis
George A Jelinek, Claudia H Marck, Tracey J Weiland, Naresh Pereira, Dania M van der Meer, Emily J Hadgkiss
BMC NEUROLOGY | BMC | Published : 2015
BACKGROUND: A growing evidence base implicates vitamin D, sun exposure and latitude in the aetiology of multiple sclerosis (MS), however there are less data on the associations of these variables with disease outcomes. METHODS: We undertook a cross-sectional survey of over 2000 people with MS recruited through internet platforms, seeking self-reported data on geographical location, intentional sun exposure for health, and supplementation with vitamin D, among other lifestyle variables. We also requested data on health-related quality of life (MSQOL-54), self-reported doctor-diagnosed relapse rate, and disability (Patient Determined Disease Steps). Bivariate and multivariate analyses were use..View full abstract
We thank all the participants of the HOLISM study for their contribution. We also thank the Bloom Foundation and the Horne Family Foundation for their generous support of the project; neither of these foundations had any role in study design or analysis, or in submission decisions.