Journal article

Multiallelic copy number variation in the complement component 4A (C4A) gene is associated with late-stage age-related macular degeneration (AMD)

Felix Grassmann, Stuart Cantsilieris, Anja-Sabrina Schulz-Kuhnt, Stefan J White, Andrea J Richardson, Alex W Hewitt, Brendan J Vote, Denise Schmied, Robyn H Guymer, Bernhard HF Weber, Paul N Baird

Journal of Neuroinflammation | BMC | Published : 2016


Awarded by Deutsche Forschungsgemeinschaft

Awarded by National Health and Medical Research Council (NHMRC)

Awarded by NHMRC

Awarded by CIDR

Funding Acknowledgements

This study was supported in parts by the Deutsche Forschungsgemeinschaft (WE 1259/19-1 and WE 1259/19-2 to BHFW) and the Alcon Research Institute (to BHFW). PNB was supported by a National Health and Medical Research Council (NHMRC) Senior Research Fellowship (#1028444) and SC by an NHMRC CJ Martin Biomedical Fellowship (#1073726). The Centre for Eye Research Australia (CERA) receives Operational Infrastructure Support from the Victorian Government. We would like to thank the International AMD Genomics Consortium (IAMDGC, for providing the genotypes at the C2/CFB locus for our samples. The samples were genotyped as part of the IAMDGC exome-chip project supported by CIDR contract number HHSN268201200008I and funded by EY022310 (to Jonathan L. Haines) and 1X01HG006934-01 (to Goncalo R. Abecasis). We thank The Gandel Charitable Trust Sequencing Centre for the use of the sequencing facility. We thank Nicole Tindill and Melinda Cain for their assistance in the data management and patient recruitment.