Journal article
Increased hippocampus-medial prefrontal cortex resting-state functional connectivity and memory function after Tai Chi Chuan practice in elder adults
J Tao, J Liu, N Egorova, X Chen, S Sun, X Xue, J Huang, G Zheng, Q Wang, L Chen, J Kong
Frontiers in Aging Neuroscience | FRONTIERS MEDIA SA | Published : 2016
Abstract
Previous studies provide evidence that aging is associated with the decline of memory function and alterations in the hippocampal (HPC) function, including functional connectivity to the medial prefrontal cortex (mPFC). In this study, we investigated if longitudinal (12-week) Tai Chi Chuan and Baduanjin practice can improve memory function and modulate HPC resting-state functional connectivity (rs-FC). Memory function measurements and resting-state functional magnetic resonance imaging (rs-fMRI) were applied at the beginning and the end of the experiment. The results showed that (1) the memory quotient (MQ) measured by the Wechsler Memory Scale-Chinese Revision significantly increased after ..
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Awarded by National Center for Complementary and Integrative Health
Funding Acknowledgements
This study is supported by the Special Scientific Research Fund of Public Welfare Profession of China (Grant No. 201307004), Ministry of Science and Technology and Ministry of Finance of the People's Republic of China, National Rehabilitation Research Center of Traditional Chinese Medicine, Fujian Provincial Rehabilitation Industrial Institution, and Fujian Rehabilitation Tech Co-Innovation Center (Grant No. X2012007-Collaboration). JK is supported by R01AT006364 (NIH/NCCIH), R01 AT008563 (NIH/NCCIH), R21AT008707 (NIH/NCCIH), and P01 AT006663 (NIH/NCCIH). We thank the Joel Park from MGH for English editing.