An X-ray fluorescence microscopic analysis of the tissue surrounding the multi-channel cochlear implant electrode array.
Kathryn Spiers, Tina Cardamone, John B Furness, Jonathan CM Clark, James F Patrick, Graeme M Clark
Cochlear Implants Int | Published : 2016
OBJECTIVES: The aim of this study was to analyse the tissue surrounding the University of Melbourne's (UOMs) multi-channel cochlear implant electrode array and cochlear limited replacements, after long-term implantations. In particular, it aimed to identify the particulate material in the fibrous tissue capsule of the arrays implanted in 1978, 1983, and 1998, by using the Australian Synchrotron for X-ray fluorescence microscopy (XFM) to reveal the characteristic spectrum of metal, in particular platinum. This also helped to determine its format and chemical state. Tissue was retrieved following the recipient's death in 2007. METHODS: Tissue was fixed and sections taken across the UOM and Coc..View full abstract