Journal article
The D-Health Trial: A randomized trial of vitamin D for prevention of mortality and cancer
RE Neale, BK Armstrong, C Baxter, B Duarte Romero, P Ebeling, DR English, MG Kimlin, DSA McLeod, RL O'Connell, JC van der Pols, AJ Venn, PM Webb, DC Whiteman, L Wockner
Contemporary Clinical Trials | Published : 2016
Abstract
Background: Vitamin D, specifically serum 25(OH)D has been associated with mortality, cancer and multiple other health endpoints in observational studies, but there is a paucity of clinical trial evidence sufficient to determine the safety and effectiveness of population-wide supplementation. We have therefore launched the D-Health Trial, a randomized trial of vitamin D supplementation for prevention of mortality and cancer. Here we report the methods and describe the trial cohort. Methods: The D-Health Trial is a randomized placebo-controlled trial, with planned intervention for 5 years and a further 5 years of passive follow-up through linkage with health and death registers. Participants ..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
The D-Health Trial is funded by a National Health and Medical Research Council (NHMRC) project grant (APP1046681) RE Neale, DSA McLeod, PM Webb and DC Whiteman are supported by fellowships from the NHMRC.