Journal article
Residential greenness is differentially associated with childhood allergic rhinitis and aeroallergen sensitization in seven birth cohorts
E Fuertes, I Markevych, G Bowatte, O Gruzieva, U Gehring, A Becker, D Berdel, A von Berg, A Bergström, M Brauer, B Brunekreef, I Brüske, C Carlsten, M Chan-Yeung, SC Dharmage, B Hoffmann, C Klümper, GH Koppelman, A Kozyrskyj, M Korek Show all
Allergy European Journal of Allergy and Clinical Immunology | WILEY | Published : 2016
DOI: 10.1111/all.12915
Abstract
Background: The prevalence of allergic rhinitis is high, but the role of environmental factors remains unclear. We examined cohort-specific and combined associations of residential greenness with allergic rhinitis and aeroallergen sensitization based on individual data from Swedish (BAMSE), Australian (MACS), Dutch (PIAMA), Canadian (CAPPS and SAGE), and German (GINIplus and LISAplus) birth cohorts (n = 13 016). Methods: Allergic rhinitis (doctor diagnosis/symptoms) and aeroallergen sensitization were assessed in children aged 6–8 years in six cohorts and 10–12 years in five cohorts. Residential greenness was defined as the mean Normalized Difference Vegetation Index (NDVI) in a 500-m buffer..
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Awarded by Federal Ministry for Environment (IUF)
Awarded by European Community
Funding Acknowledgements
The BAMSE study was supported by the Swedish Research Council, the Swedish Heart-Lung Foundation, Stiftelsen Frimurare Barnhuset i Stockholm, Matsumura's donation, the Stockholm County Council, the Swedish Environmental Protection Agency, the Swedish Society for Medical Research, the Swedish Foundation for Strategic Research, and the Swedish Research Council for Health Working Life and Welfare. The PIAMA study is supported by The Netherlands Organization for Health Research and Development, The Netherlands Organization for Scientific Research, The Netherlands Asthma Fund, The Netherlands Ministry of Spatial Planning, Housing, and the Environment, and The Netherlands Ministry of Health, Welfare and Sport. The GINIplus study was mainly supported for the first 3 years by the Federal Ministry for Education, Science, Research and Technology (interventional arm) and Helmholtz Zentrum Munich (former GSF) (observational arm). The 4-year, 6-year, and 10-year follow-up examinations of the GINIplus study were covered from the respective budgets of the 5 study centers (Helmholtz Zentrum Munich (former GSF), Marien-Hospital Wesel, LMU Munich, TU Munich and from 6 years onward also from IUF-Leibniz Research Institute for Environmental Medicine) and a grant from the Federal Ministry for Environment (IUF, FKZ 20462296). The LISAplus study was mainly supported by grants from the Federal Ministry for Education, Science, Research and Technology and in addition from Helmholtz Zentrum Munich (former GSF), Helmholtz Centre for Environmental Research-UFZ, Leipzig, Marien-Hospital Wesel, Pediatric Practice, Bad Honnef for the first 2 years. The 4-year, 6-year, and 10-year follow-up examinations of the LISAplus study were covered from the respective budgets of the involved partners (Helmholtz Zentrum Munich (former GSF), Helmholtz Centre for Environmental Research-UFZ, Leipzig, Marien-Hospital Wesel, Pediatric Practice, Bad Honnef, IUF-Leibniz Research Institute for Environmental Medicine) and in addition by a grant from the Federal Ministry for Environment (IUF, FKZ 20462296). The CAPPS study was supported by the Canadian Institutes of Health Research, the British Columbia Lung Association and the Manitoba Medical Service Foundation. The SAGE study was supported by the Canadian Institutes of Health Research. The first 6 years of the MACS study was funded by Nestec Ltd, a subsidiary of Nestle Australia. The 12-year follow-up was funded by a project grant from the Asthma Foundation of Victoria. The NHMRC funded Centre for Air Quality and Health Research and evaluation (CAR) funded geocoding of participants' addresses. The 'Traffic Asthma and Genetics' collaboration was supported by the AllerGen Networks of Centres of Excellence. The ESCAPE (grant agreement number: 211250) research received funding from the European Community's Seventh Framework Program (FP7/2007-2011). The aforementioned funding sources had no involvement in the study design, in the collection, analysis, and interpretation of data, in the writing of the report and in the decision to submit the article for publication.