Dissociating the therapeutic effects of environmental enrichment and exercise in a mouse model of anxiety with cognitive impairment

J Rogers; U Vo; LS Buret; TY Pang; H Meiklejohn; A Zeleznikow-Johnston; L Churilov; M van den Buuse; AJ Hannan; T Renoir

Journal article

Dissociating the therapeutic effects of environmental enrichment and exercise in a mouse model of anxiety with cognitive impairment

J Rogers, U Vo, LS Buret, TY Pang, H Meiklejohn, A Zeleznikow-Johnston, L Churilov, M van den Buuse, AJ Hannan, T Renoir

TRANSLATIONAL PSYCHIATRY | NATURE PUBLISHING GROUP | Published : 2016

DOI: 10.1038/tp.2016.52

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University of Melbourne Researchers

Thibault Renoir Author Florey Department of Neuroscience and Mental Health

Terence Pang Author Physiology

Anthony Hannan Author Florey Department of Neuroscience and Mental Health

Leonid Churilov Author Medicine - Austin Health

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Funding Acknowledgements

We thank Dr M Ransome for technical assistance (BrdU and Ki67 immunochemistry), as well as Tine Pooters for help in implementing our water maze cue set-up. We also thank Drs A Garthe and G Kempermann for providing the MATLAB script, as well as Matt Hudson for helping to analyse the search strategy in the Morris water maze. This work was supported by an ARC FT3 Future Fellowship (AJH) and ARC Discovery Early Career Research Award (TR). AJH is a NHMRC Senior Research Fellow. The Florey Institute of Neuroscience and Mental Health acknowledge the support from the Victorian Government's Operational Infrastructure Support Grant.