Journal article

The changing survival profile of people with Down's syndrome: implications for genetic counselling

EJ Glasson, SG Sullivan, R Hussain, BA Petterson, PD Montgomery, AH Bittles

Clinical Genetics | BLACKWELL MUNKSGAARD | Published : 2002

Abstract

Cohort studies have indicated that the survival of individuals with Down's syndrome has dramatically increased over the past 50 years. Early childhood survival in particular has shown major improvement, due largely to advances in cardiac surgery and in general health management. The present study was based on a continuous cohort of 1332 people with Down's syndrome in Western Australia, registered for intellectual disability services between 1953 and 2000. Their life expectancy was 58.6 years, 25% lived to 62.9 years, and the oldest living person is 73 years of age. Life expectancy for males was greater than females by 3.3 years. The substantial increase in survival across the study period me..

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University of Melbourne Researchers