Journal article
Perinatal risk factors associated with the obstructive sleep apnea syndrome in school-aged children born preterm
IE Tapia, J Shults, LW Doyle, GM Nixon, CM Cielo, J Traylor, CL Marcus
Sleep | Published : 2016
DOI: 10.5665/sleep.5618
Abstract
Study Objectives: The obstructive sleep apnea syndrome (OSAS) is more prevalent in ex-preterm children compared to the general pediatric population. However, it is unknown whether OSAS in ex-preterm children is associated with specific perinatal risk factors. This multicenter cohort study aimed to determine perinatal factors associated with OSAS at school age. Methods: 197 ex-preterm (500-1,250 g) children aged 5-12 y who participated as neonates in a double-blind, randomized clinical trial of caffeine versus placebo (Caffeine for Apnea of Prematurity) underwent comprehensive ambulatory polysomnography. A negative binomial regression model was used to identify perinatal risk factors associat..
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Awarded by National Institutes of Health
Funding Acknowledgements
This was not an industry supported study. Funding was supplied by a National Institutes of Health grant R01 HL098045 and Canadian Institutes of Health Research grant MCT 13288. Dr. Marcus has received research support from Philips Respironics in the form of loaned equipment. The other authors have indicated no financial conflicts of interest.