Microsatellite Genotyping of Plasmodium vivax Isolates from Pregnant Women in Four Malaria Endemic Countries
Michela Menegon, Azucena Bardaji, Flor Martinez-Espinosa, Camila Botto-Menezes, Maria Ome-Kaius, Ivo Mueller, Inoni Betuela, Myriam Arevalo-Herrera, Swati Kochar, Sanjay K Kochar, Puneet Jaju, Dhiraj Hans, Chetan Chitnis, Norma Padilla, Maria Eugenia Castellanos, Lucia Ortiz, Sergi Sanz, Mireia Piqueras, Meghna Desai, Alfredo Mayor Show all
PLoS One | PUBLIC LIBRARY SCIENCE | Published : 2016
Plasmodium vivax is the most widely distributed human parasite and the main cause of human malaria outside the African continent. However, the knowledge about the genetic variability of P. vivax is limited when compared to the information available for P. falciparum. We present the results of a study aimed at characterizing the genetic structure of P. vivax populations obtained from pregnant women from different malaria endemic settings. Between June 2008 and October 2011 nearly 2000 pregnant women were recruited during routine antenatal care at each site and followed up until delivery. A capillary blood sample from the study participants was collected for genotyping at different time points..View full abstract
Awarded by EU
The PregVax collaborative project was an EU-FP7 funded programme (FP7-HEALTH-201588). This research was also supported by the Malaria in Pregnancy Consortium, which is funded through a grant from the Bill and Melinda Gates Foundation to the Liverpool School of Tropical Medicine. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.