Journal article
A randomized controlled trial of very early rehabilitation in speech after stroke
E Godecke, EA Armstrong, T Rai, S Middleton, N Ciccone, A Whitworth, M Rose, A Holland, F Ellery, GJ Hankey, DA Cadilhac, J Bernhardt
International Journal of Stroke | SAGE PUBLICATIONS LTD | Published : 2016
Abstract
Rationale: The efficacy of rehabilitation therapy for aphasia caused by stroke is uncertain. Aims and hypothesis: The Very Early Rehabilitation of Speech (VERSE) trial aims to determine if intensive prescribed aphasia therapy (VERSE) is more effective and cost saving than non-prescribed, intensive (usual care-plus) and non-intensive usual care (UC) therapy when started within 15 days of stroke onset and continued daily over four weeks. We hypothesize that aphasia therapy when started very early after stroke and delivered daily could enhance recovery of communication compared with UC. Sample size estimates: A total of 246 participants (82 per arm) will provide 80% power to detect a 4.4% impro..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The VERSE trials are supported by a National Health and Medical Research Council project grant (1044973). DC is supported by an NHMRC Public Health /National Heart Foundation Future Leader Research Fellowship (1063761).