Journal article

Characterization of a hepatitis C virus-like particle vaccine produced in a human hepatocyte-derived cell line

L Earnest-Silveira, B Chua, R Chin, D Christiansen, D Johnson, S Herrmann, SA Ralph, K Vercauteren, A Mesalam, P Meuleman, S Das, I Boo, H Drummer, C-T Bock, EJ Gowans, DC Jackson, Joseph Torresi

Journal of General Virology | MICROBIOLOGY SOC | Published : 2016


Awarded by National Health and Medical Research Council (NHMRC) of Australia

Awarded by Australian Center for HIV and Heptitis Virology

Awarded by Australia-India Biotechnology Research Fund

Awarded by NHMRC Practitioner Fellowship

Awarded by NHMRC

Awarded by NHMRC Career Development Fellowship

Funding Acknowledgements

This work was supported by research grants from the National Health and Medical Research Council (NHMRC) of Australia (project grant APP1060436), Australian Center for HIV and Heptitis Virology (ACH2), Commonwealth Department of Health and Aged Care, Australia; Australia-India Biotechnology Research Fund (BF040005), Department of Innovation and Industry, Australian Commonwealth Government. J.T. is supported by an NHMRC Practitioner Fellowship (APP1060433) and E.G. by a NHMRC Senior Research Fellow award (grant number 543139) and S.R. by a NHMRC Career Development Fellowship (APP1062504). We wish to thank Professor Hanswalter Zentgraf, Heidelberg University, Germany, for performing the immunogold electron microscopy. We wish to thank Dr Eric Hanssen, The University of Melbourne, for assistance with electron tomography. Experiments involving animals were approved by the animal ethics committee of the University of Melbourne (AEC numbers 0707207 and 061061). Experiments involving human sera collected from HCVinfected individuals and de-identified prior to use were approved by HREC of Melbourne Health, Parkville, Australia (HREC 2003.258). The authors have no conflicts of interest to declare.