Journal article

Ixodes scapularis and Ixodes ricinus tick cell lines respond to infection with tick-borne encephalitis virus: transcriptomic and proteomic analysis

Sabine Weisheit, Margarita Villar, Hana Tykalova, Marina Popara, Julia Loecherbach, Mick Watson, Daniel Ruzek, Libor Grubhoffer, Jose de la Fuente, John K Fazakerley, Lesley Bell-Sakyi

Parasites & Vectors | BIOMED CENTRAL LTD | Published : 2015

Grants

Awarded by POSTICK ITN (Post-graduate training network for capacity building to control ticks and tick-borne diseases) within the FP7- PEOPLE- ITN programme (EU)


Awarded by Ministerio de Economia y Competitividad, Spain


Awarded by European Union FP7 ANTIGONE project


Awarded by Czech Science Foundation (GACR)


Awarded by Biology Centre ASCR, Institute of Parasitology


Awarded by Czech Science Foundation


Awarded by MEYS of the Czech Republic under the NPU I programme


Awarded by Biotechnology and Biological Sciences Research Council


Awarded by Medical Research Council


Awarded by Natural Environment Research Council


Funding Acknowledgements

The authors would like to thank the Tick Cell Biobank at The Pirbright Institute (http://www.pirbright.ac.uk/research/tickcell/Default.aspx) and Dr Ulrike Munderloh of the University of Minnesota for provision of tick cell lines, Dr Sonja Best of the Rocky Mountain Laboratories, NIAID, NIH, Hamilton, Montana and Dr Esther Schnettler of the University of Glasgow for provision of the TP21 strain of Langat virus, and Dr Christian Mandl and Prof. Franz Heinz of the Medical University of Vienna for provision of the Neudoerfl strain of tick-borne encephalitis virus and the pTND/Delta ME plasmid. SW and MP were Early Stage Researchers supported by the POSTICK ITN (Post-graduate training network for capacity building to control ticks and tick-borne diseases) within the FP7- PEOPLE- ITN programme (EU Grant No. 238511). The research was supported by: grants BFU2011-23896 from the Ministerio de Economia y Competitividad, Spain and the European Union FP7 ANTIGONE project number 278976 (MV, JF); the Czech Science Foundation (GACR) (15-03044S) and by Institutional support RVO: 60077344 from Biology Centre ASCR, Institute of Parasitology (HT, LG); the Czech Science Foundation (projects nos P502/11/2116 and GA14-29256S) and the MEYS of the Czech Republic (project LO1218) under the NPU I programme (DR); the United Kingdom Biotechnology and Biological Sciences Research Council's National Capability Grant to the Pirbright Institute (LBS). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.