Journal article

Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern

N Matigian, G Brooke, F Zaibak, T Rossetti, K Kollar, R Pelekanos, C Heazlewood, A Mackay-Sim, CA Wells, K Atkinson

Genomics Data | ELSEVIER SCIENCE BV | Published : 2015

Abstract

Multipotent mesenchymal stromal cells derived from human placenta (pMSCs), and unrestricted somatic stem cells (USSCs) derived from cord blood share many properties with human bone marrow-derived mesenchymal stromal cells (bmMSCs) and are currently in clinical trials for a wide range of clinical settings. Here we present gene expression profiles of human cord blood-derived unrestricted somatic stem cells (USSCs), human placental-derived mesenchymal stem cells (hpMSCs), and human bone marrow-derived mesenchymal stromal cells (bmMSCs), all derived from four different donors. The microarray data are available on the ArrayExpress database (. www.ebi.ac.uk/arrayexpress) under accession number E-T..

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University of Melbourne Researchers

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Funding Acknowledgements

The authors kindly acknowledge funding provided by the Australian Federal Government Department of Health and Ageing (AMS) and the Australian Research Council Special Research Initiative to Stem Cells Australia (CW). CW is the recipient of a Queensland Smart Futures Fellowship; NM is a recipient of an Australian Postgraduate Award. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Funding was also provided by the Australian Stem Cell Centre, The Heart Foundation, The Mater Foundation and Inner Wheel Australia. CH and KK were recipients of PhD scholarships from The University of Queensland and the Queensland University of Technology respectively. The authors would also like to thank Robert Williamson for his enthusiastic support of this study.