N-acetylcysteine modulates glutamatergic dysfunction and depressive behavior in Huntington's disease

Dean J Wright; Laura J Gray; David I Finkelstein; Peter J Crouch; David Pow; Terence Y Pang; Shanshan Li; Zoe M Smith; Paul S Francis; Thibault Renoir; Anthony J Hannan

Journal article

N-acetylcysteine modulates glutamatergic dysfunction and depressive behavior in Huntington's disease

Dean J Wright, Laura J Gray, David I Finkelstein, Peter J Crouch, David Pow, Terence Y Pang, Shanshan Li, Zoe M Smith, Paul S Francis, Thibault Renoir, Anthony J Hannan

Human Molecular Genetics | OXFORD UNIV PRESS | Published : 2016

DOI: 10.1093/hmg/ddw144

University of Melbourne Researchers

Thibault Renoir Author Florey Department of Neuroscience and Mental Health

Peter Crouch Author Pharmacology and Therapeutics

David Finkelstein Author Florey Department of Neuroscience and Mental Health

Terence Pang Author Physiology

Anthony Hannan Author Florey Department of Neuroscience and Mental Health

Related Projects (1)

Mechanisms Mediating The Beneficial Effects Of N-Acetylcysteine In Huntington’S Disease.

Grants

Funding Acknowledgements

This work was supported by an Australian Research Council (ARC) FT3 Future Fellowship (A.J.H.) and National Health and Medical Research Council (NHMRC) Project Grant (A.J.H., T.R. and P.J.C.), as well as a philanthropic grant from the Macquarie Foundation (A.J.H.). A.J.H. is an NHMRC Senior Research Fellow, T.R. is an ARC DECRA Fellow and P.J.C. is an NHMRC Career Development Fellow.