Journal article
Findings and Outcomes in a Prevaccination Cohort of Women Younger Than 25 Years Attending a Tertiary Colposcopy Service
YL Jayasinghe, R Bhat, M Quinn, CDH Wrede, JHJ Tan
Journal of Lower Genital Tract Disease | LIPPINCOTT WILLIAMS & WILKINS | Published : 2016
Abstract
Objective To describe clinical presentation and treatment in women younger than 25 years referred to the Royal Women's Hospital colposcopy clinic, before implementation of the National Human Papillomavirus Vaccination Program. Methods Retrospective cohort analysis of women younger than 25 years referred to a tertiary hospital colposcopy clinic between 1998 and 2007. Clinical presentation and correlation between cervical cytology, biopsy, and histology at treatment was examined. Results Approximately 14,635 colposcopies were undertaken in 4104 women (median age, 22 years); 3051 had abnormal referral cytology, of whom, 23.8% had high-grade disease on punch biopsy. High-grade disease was found ..
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Funding Acknowledgements
No funding sources to disclose. The authors have no financial or commercial interests with respect to the material in this paper nor do they have any conflicts of interest to declare. Dr Jayasinghe has been provided with scholarship support from RANZCOG Research Foundation, Cancer Council of Victoria, the Royal Australasian College of Physicians (Novartis Scholarship for Sexual Health Research), and grant support from the Victorian Cancer Agency for examining risk factors for cervical cancer in young women and unrelated studies. Mr. Wrede is an Honorary Board member of the Victorian Cytology Service, which performs more than 50% of the cervical cytology in Victoria. He is also a member of the multidisciplinary working party for the development of clinical management guidelines for the prevention of cervical cancer.