Journal article
Childhood infections, socioeconomic status, and adult cardiometabolic risk
RS Liu, DP Burgner, MA Sabin, CG Magnussen, M Cheung, N Hutri-Kähönen, M Kähönen, T Lehtimäki, E Jokinen, T Laitinen, L Taittonen, T Dwyer, JSA Viikari, M Kivimäki, OT Raitakari, M Juonala
Pediatrics | AMER ACAD PEDIATRICS | Published : 2016
Abstract
BACKGROUND AND OBJECTIVES: Socioeconomic disadvantage throughout the life course is abstract associated with increased risk of cardiometabolic diseases, but traditional risk factors do not fully account for the social gradient. We investigated the interactions between low socioeconomic status (SES) and infection in childhood and adverse cardiometabolic parameters in adulthood. METHODS: Participants from the Cardiovascular Risk in Young Finns Study, a cohort well phenotyped for childhood and adulthood cardiometabolic risk factors and socioeconomic parameters, were linked to lifetime hospitalization data from birth onward available from the Finnish National Hospital Registry. In those with com..
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Awarded by Tampereen Tuberkuloosisäätiö
Funding Acknowledgements
This work within the Cardiovascular Risk in Young Finns Study has been financially supported by the Academy of Finland; the Social Insurance Institution of Finland; the Kuopio, Tampere, and Turku University Hospital Medical Funds; the Paulo Foundation; the Juho Vainio Foundation; the Paavo Nurmi Foundation; the Finnish Foundation of Cardiovascular Research; the Finnish Cultural Foundation, the Finnish Medical Foundation, the Sigrid Juselius Foundation; Maud Kuistila Foundation; and the Tampere Tuberculosis Foundation, Emil Aaltonen Foundation, and Yrjo Jahnsson Foundation. Drs Liu, Burgner, Sabin, and Magnussen are supported by National Health and Medical Research Council (Canberra, Australia) fellowships and scholarships. Dr Burgner is an Honorary Future Leader Fellow of the National Heart Foundation of Australia. Dr Kivimaki is supported by the Medical Research Council (grant K013351), the Economic and Social Research Council, and NordForsk, the Nordic Council of Ministers (grant 75021). Drs Juonala, Sabin, and Magnussen are supported by the National Health and Medical Research Council (Canberra, Australia) (grant 1098369). Research at Murdoch Childrens Research Institute is supported by the Victorian Government's Operational Infrastructure Support Program (Melbourne, Australia). The Heart Research Group at Murdoch Childrens Research Institute is supported by the Royal Children's Hospital (RCH) Foundation (Melbourne, Australia).