ICU-acquired candidemia within selective digestive decontamination studies: a meta-analysis
James C Hurley
INTENSIVE CARE MEDICINE | SPRINGER | Published : 2015
PURPOSE: To estimate the direct and indirect (contextual) effects of the factorized constituents of selective digestive decontamination and selective oropharyngeal decontamination (SDD/SOD), being topical antibiotic (TA) and protocolized antifungal prophylaxis (PAFP), on ICU-acquired candidemia. METHODS: A broad range of ICU candidemia incidence studies were sourced to serve as points of reference. The candidemia incidence was extracted from component (control and intervention) groups decanted from studies of various designs (concurrent or non-concurrent) and whether investigating SDD/SOD versus non-TA methods of ICU infection prevention. The candidemia incidences were summarized in regressi..View full abstract
This work was supported by the Australian Government Department of Health and Ageing through the Rural Clinical Training and Support (RCTS) program.