Journal article

Adiposity assessed by anthropometric measures has a similar or greater predictive ability than dual-energy X-ray absorptiometry measures for abdominal aortic calcification in community-dwelling older adults

Xianwen Shang, David Scott, Allison Hodge, Belal Khan, Nayab Khan, Dallas R English, Graham G Giles, Peter R Ebeling, Kerrie M Sanders



To determine whether adiposity assessed by dual-energy X-ray absorptiometry (DXA) compared to simple anthropometric assessments, are more predictive of abdominal aortic calcification (AAC), a risk factor for atherosclerosis. A cross-sectional study of 312 participants (60.3 % female) aged 70.6 ± 5.6 years was conducted in 2010-2011. AAC was assessed by radiography. Adiposity was estimated for whole body, trunk, android, gynoid and visceral regions using DXA in addition to body mass index (BMI), waist circumference (WC) and waist to hip ratio (WHR). WHR [tertile 1 as reference, OR (95 % CI) for tertile 3: 3.62 (1.35-9.72)] and android to gynoid fat ratio [tertile 3: 2.87 (1.03-8.01)] were ind..

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Awarded by Australian NHMRC

Funding Acknowledgements

This study was funded by the Department of Medicine, Western Hospital and the University of Melbourne Research Grant Scheme and a Heart Foundation Grant. The Melbourne Collaborative Cohort Study is funded by VicHealth and Cancer Council Victoria and further supported by Australian NHMRC Grants 209057, 251553 and 504711 and by infrastructure provided by Cancer Council Victoria. We thank the other investigators, staff, and participants of the Melbourne Collaborative Cohort Study cohort for their important contributions.