Journal article

Predictive Factors for Verbal Memory Performance Over Decades of Aging: Data from the Women's Healthy Ageing Project

Cassandra Szoeke, Philippe Lehert, Victor W Henderson, Lorraine Dennerstein, Patricia Desmond, Stephen Campbell

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY | ELSEVIER SCIENCE INC | Published : 2016

Abstract

BACKGROUND: Abnormalities in brain structure and function can occur several decades prior to the onset of cognitive decline. It is in the preceding decades that an intervention is most likely to be effective, when informed by an understanding of factors contributing to the disease prodrome. Few studies, however, have sufficient longitudinal data on relevant risks to determine the optimum targets for interventions to improve cognition in aging. In this article we examine the timing and exposure of factors contributing to verbal memory performance in later life. METHODS: 387 participants from the population-based Women's Healthy Ageing Project, mean age at baseline of 49.6 years (range: 45-55 ..

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Grants

Awarded by National Health and Medical Research Council (NHMRC)


Awarded by Alzheimer's Association


Awarded by NATIONAL INSTITUTE ON AGING


Funding Acknowledgements

We would like to acknowledge the contribution of the participants and their supporters who have contributed their time and patience for over 20 years to the University. A full list of all researchers contributing to the project and the membership of our Scientific Advisory Board is available at http://www.medrmhwh.unimelb.edu.au/Research/WHAP.html. We are thankful to our participants, team, partners, and supporters for making this study of now more than 20 years possible. Funding for the WHAP has been provided by the National Health and Medical Research Council (NHMRC grants 547500, 1032350, and 1062133), the Ramaciotti Foundations, the Brain Foundation, the Alzheimer's Association (NIA320312), the Australian Menopausal Society, Bayer HealthCare, the Shepherd Foundation, the Scobie and Claire Mackinnon Trust, the Collier Trust Fund, the J. O. and J. R. Wicking Trust, and the Mason Foundation.The principal investigator of WHAP (CSz) is supported by the National Health and Medical Research Council and the Faculty of Medicine, Dentistry, and Health Sciences at the University of Melbourne.