Journal article

Understanding the Pathogenicity of Noncoding Mismatch Repair Gene Promoter Variants in Lynch Syndrome

Qing Liu, Bryony A Thompson, Robyn L Ward, Luke B Hesson, Mathew A Sloane

Human Mutation | WILEY | Published : 2016

DOI: 10.1002/humu.22971

University of Melbourne Researchers

Related Projects (1)

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Identification Of Novel Colorectal Cancer Susceptibility Genes

Colon cancer is one of the most common cancers, with around 1 million cases diagnosed annually. These cancers can be caused by a combination..

Grants

Awarded by Cancer Institute NSW

Awarded by NHMRC Early-Career Fellowship

Funding Acknowledgements

Contract grant sponsors: Cancer Institute NSW (to R. L. D.); Cancer Council NSW (RG13-07 to R. L. D.); NHMRC Early-Career Fellowship (1091211 to B. A. T.).

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2Web of Science
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Keywords

Noncoding Variant
Genetic Variation
Promoter
5 ' Utr
Colorectal Neoplasms, Hereditary Nonpolyposis
Transcription Factor
10-Mb Paracentric Inversion
Promoter Regions, Genetic
Genetic Predisposition To Disease
Humans
Mlh1 Epimutation
Gene Expression Regulation, Neoplastic
Methylation
Nonpolyposis Colorectal-Cancer
Expression
Dna-Binding Proteins
5′ Utr
Mutations
Cancer Susceptibility
Life Sciences & Biomedicine
Lynch Syndrome
X-Chromosome
Muts Homolog 2 Protein
Mismatch Repair Endonuclease Pms2
Sequence Variants
Dna Mismatch Repair
Msh2 Genes
Science & Technology
Mutl Protein Homolog 1
Genetics & Heredity