Journal article

Effects of pulsatile electrical stimulation of the round window on central hyperactivity after cochlear trauma in guinea pig

WHAM Mulders, TC Spencer, D Robertson

HEARING RESEARCH | ELSEVIER SCIENCE BV | Published : 2016

Abstract

Partial hearing loss induced by acoustic trauma has been shown in animal models to result in an increased spontaneous firing rate in central auditory structures. This so-called hyperactivity has been suggested to be involved in the generation of tinnitus, a phantom auditory sensation. Although there is no universal cure for tinnitus, electrical stimulation of the cochlea, as achieved by a cochlear implant, can result in significant reduction of the tinnitus percept. However, the mechanism by which this tinnitus suppression occurs is as yet unknown and furthermore cochlear implantation may not be an optimal treatment option for tinnitus sufferers who are not profoundly deaf. A better understa..

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University of Melbourne Researchers