Journal article

A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1

Mohammed Akhter Hossain, Martina Kocan, Song T Yao, Simon G Royce, Vinojini B Nair, Christopher Siwek, Nitin A Patil, Ian P Harrison, K Johan Rosengren, Stavros Selemidis, Roger J Summers, John D Wade, Ross AD Bathgate, Chrishan S Samuel

Chemical Science | ROYAL SOC CHEMISTRY | Published : 2016


Awarded by National Health & Medical Research Council (NHMRC) of Australia

Awarded by NHMRC

Awarded by ARC

Awarded by Australian Future Fellowships

Funding Acknowledgements

This work was supported by National Health & Medical Research Council (NHMRC) of Australia Grants (GNT1023321, GNT1023078, and GNT1065481) awarded to M. A. H., J. D. W., K. J. R., and R. A. D. B., (GNT1050268 and GNT1079680) awarded to S. T. Y., a NHMRC Program Grant GNT1055134 and ARC Linkage grant LP110100288 to R. J. S., a Florey Foundation Fellowship and Melbourne Research Grant Support Scheme (RGSS) awarded to M. A. H., a University of Melbourne Postgraduate Scholarship to V. B. N. and N. A. P., an Australian Postgraduate Award to C. S., Australian Future Fellowships to K. J. R. (FT130100890) and S. S. (FT120100876), an NHMRC Principal Research Fellowship to J. D. W. (GNT5018148) and NHMRC Senior Research Fellowships to R. A. D. B. (GNT1042650) and C. S. S. (GNT1041766). Research at The Florey Institute of Neuroscience and Mental Health is supported by the Victorian Government Operational Infrastructure Support Program. We sincerely thank Mr Sharon Layfield, Ms Tania Ferraro and Ms Kazi Jannatul Ferdous for expert technical assistance; Associate Professor Tim Hewitson (Royal Melbourne Hospital, Melbourne, Australia) for providing the rat renal myofibroblasts; and Professor Robert Widdop (Monash University, Melbourne, Australia) for providing the PD123319.