Journal article

Clinical and functional differences between early-onset and late-onset adult asthma: A population-based Tasmanian Longitudinal Health Study

DJ Tan, EH Walters, JL Perret, JA Burgess, DP Johns, AJ Lowe, CJ Lodge, P Hayati Rezvan, JA Simpson, S Morrison, BR Thompson, PS Thomas, I Feather, GG Giles, JL Hopper, MJ Abramson, MC Matheson, SC Dharmage

Thorax | BMJ PUBLISHING GROUP | Published : 2016

Abstract

Background Differences between early-onset and late-onset adult asthma have not been comprehensively described using prospective data. Aims To characterise the differences between early-onset and late-onset asthma in a longitudinal cohort study. Methods The Tasmanian Longitudinal Health Study (TAHS) is a population-based cohort. Respiratory histories and spirometry were first performed in 1968 when participants were aged 7 (n=8583). The cohort was traced and resurveyed from 2002 to 2005 (n=5729 responses) and a sample, enriched for asthma and bronchitis participated in a clinical study when aged 44 (n=1389). Results Of the entire TAHS cohort, 7.7% (95% CI 6.6% to 9.0%) had early-onset and 7...

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