Examining maintenance care following infliximab salvage therapy for acute severe ulcerative colitis

D Seah; MC Choy; A Gorelik; WR Connell; MP Sparrow; D Van Langenberg; G Hebbard; G Moore; P De Cruz

Conference Proceedings

Examining maintenance care following infliximab salvage therapy for acute severe ulcerative colitis

D Seah, MC Choy, A Gorelik, WR Connell, MP Sparrow, D Van Langenberg, G Hebbard, G Moore, P De Cruz

Journal of Gastroenterology and Hepatology Australia | WILEY | Published : 2018

DOI: 10.1111/jgh.13850

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Abstract

Background and Aim: Data supporting the optimal maintenance drug therapy and strategy to monitor ongoing response following successful infliximab (IFX) induction, for acute severe ulcerative colitis (ASUC), are limited. We aimed to evaluate maintenance and monitoring strategies employed in patients post-IFX induction therapy. Methods: Patients in six Australian tertiary centers treated with IFX for steroid-refractory ASUC between April 2014 and May 2015 were identified via hospital IBD and pharmacy databases. Patients were followed up for 1 year with clinical data over 12 months recorded. Analysis was limited to patient outcomes beyond 3 months. Results: Forty one patients were identified. F..

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University of Melbourne Researchers

Alex Gorelik Author

William Connell Author

Geoffrey Hebbard Author

Matthew Choy Author

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ACUTE SEVERE ULCERATIVE COLITIS - CLINICAL AND TRANSLATIONAL STUDIES

One in five patients with severe ulcerative colitis, a condition resulting in damage to the large bowel, may require surgery to remove the b..

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Funding Acknowledgements

M. C. C. is supported by an Australian Postgraduate Award scholarship from the University of Melbourne. P. D. C. is supported by a David Bickart Clinician Research Award from the University of Melbourne and Bushell Postdoctoral Award from the Gastroenterological Society of Australia.