Journal article

Clinical application of low-dose phase contrast breast CT: methods for the optimization of the reconstruction workflow

S Pacile, F Brun, C Dullin, YI Nesterest, D Dreossi, S Mohammadi, M Tonutti, F Stacul, D Lockie, F Zanconati, A Accardo, G Tromba, TE Gureyev

BIOMEDICAL OPTICS EXPRESS | OPTICAL SOC AMER | Published : 2015

Abstract

Results are presented of a feasibility study of three-dimensional X-ray tomographic mammography utilising in-line phase contrast. Experiments were performed at SYRMEP beamline of Elettra synchrotron. A specially designed plastic phantom and a mastectomy sample containing a malignant lesion were used to study the reconstructed image quality as a function of different image processing operations. Detailed evaluation and optimization of image reconstruction workflows have been carried out using combinations of several advanced computed tomography algorithms with different pre-processing and post-processing steps. Special attention was paid to the effect of phase retrieval on the diagnostic valu..

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University of Melbourne Researchers