Clinical application of low-dose phase contrast breast CT: methods for the optimization of the reconstruction workflow
S Pacile, F Brun, C Dullin, YI Nesterest, D Dreossi, S Mohammadi, M Tonutti, F Stacul, D Lockie, F Zanconati, A Accardo, G Tromba, TE Gureyev
BIOMEDICAL OPTICS EXPRESS | OPTICAL SOC AMER | Published : 2015
Results are presented of a feasibility study of three-dimensional X-ray tomographic mammography utilising in-line phase contrast. Experiments were performed at SYRMEP beamline of Elettra synchrotron. A specially designed plastic phantom and a mastectomy sample containing a malignant lesion were used to study the reconstructed image quality as a function of different image processing operations. Detailed evaluation and optimization of image reconstruction workflows have been carried out using combinations of several advanced computed tomography algorithms with different pre-processing and post-processing steps. Special attention was paid to the effect of phase retrieval on the diagnostic valu..View full abstract
Awarded by EXTREMA COST Action
Networking support was provided by the EXTREMA COST Action MP1207. The authors would like to thank Dr. Nicola Sodini of Elettra-Sincrotrone Trieste for manufacturing the plastic phantom used in this study.