Journal article
Investigation of the imaging quality of synchrotron-based phase-contrast mammographic tomography
TE Gureyev, SC Mayo, YI Nesterets, S Mohammadi, D Lockie, RH Menk, F Arfelli, KM Pavlov, MJ Kitchen, F Zanconati, C Dullin, G Tromba
Journal of Physics D Applied Physics | IOP PUBLISHING LTD | Published : 2014
Abstract
We report the results of a systematic study of phase-contrast x-ray computed tomography in the propagation-based and analyser-based modes using specially designed phantoms and excised breast tissue samples. The study is aimed at the quantitative evaluation and subsequent optimization, with respect to detection of small tumours in breast tissue, of the effects of phase contrast and phase retrieval on key imaging parameters, such as spatial resolution, contrast-to-noise ratio, x-ray dose and a recently proposed 'intrinsic quality' characteristic which combines the image noise with the spatial resolution. We demonstrate that some of the methods evaluated in this work lead to substantial (more t..
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Awarded by University of New England
Funding Acknowledgements
The authors would like to thank Dr Dicgo Drcossi and Dr Nicola Sodini for their help during the experiments at the SYRMEP beamline. They are also very grateful to Mrs Cristina Bottin for expertly preparing the histological samples. The authors acknowledge travel funding provided by the International Synchrotron Access Program (ISAP) managed by the Australian Synchrotron and funded by the Australian Government. MJK acknowledges support of the Australian Research Council (ARC) and is the recipient of an ARC Australian Research Fellowship (DP110101941; DP130104913). KMP acknowledges financial support from the University of New England.