Conference Proceedings

Quantitative phase-contrast tomography using polychromatic radiation

GR Myers, TE Gureyev, DM Paganin, KKW Siu, SC Mayo, SW Wilkins

Proceedings of SPIE the International Society for Optical Engineering | SPIE-INT SOC OPTICAL ENGINEERING | Published : 2008

Abstract

We discuss theoretical, experimental and numerical aspects of several new techniques for quantitative phase-contrast tomography using, for example, unfiltered radiation from a polychromatic X-ray microfocus source. The proposed algorithms allow one to reconstruct the three-dimensional distribution of complex refractive index in a sample consisting of one or more constituent materials, given one or more projection images per view angle. If the sample is weakly absorbing or consists predominantly of a single material, these reconstruction algorithms can be simplified and fewer projections may be required for an unambiguous quantitative reconstruction of the spatial distribution of the refracti..

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University of Melbourne Researchers

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Funding Acknowledgements

Financial support from the Australian Research Council is gratefully acknowledged, for funding from both the Discovery-Project (DMP) and Australian Postgraduate Award (GRM) schemes. TEG, SCM and SWW are grateful to XRT Limited for encouragement of this work. KKWS and her collaborator Dr D. W. Parsons (Women's and Children's Hospital and Department of Paediatrics, University of Adelaide) would like to acknowledge support of the National Health and Medical Research Council and the Access to Major Research Facilities program for enabling the work carried out at the SPring-8 synchrotron in Japan.