Journal article

Minimising impairment: Protocol for a multicentre randomised controlled trial of upper limb orthoses for children with cerebral palsy

Christine Imms, Margaret Wallen, Catherine Elliott, Brian Hoare, Melinda Randall, Susan Greaves, Brooke Adair, Elizabeth Bradshaw, Rob Carter, Francesca Orsini, Sophy TF Shih, Dinah Reddihough

BMC PEDIATRICS | BMC | Published : 2016


BACKGROUND: Upper limb orthoses are frequently prescribed for children with cerebral palsy (CP) who have muscle overactivity predominantly due to spasticity, with little evidence of long-term effectiveness. Clinical consensus is that orthoses help to preserve range of movement: nevertheless, they can be complex to construct, expensive, uncomfortable and require commitment from parents and children to wear. This protocol paper describes a randomised controlled trial to evaluate whether long-term use of rigid wrist/hand orthoses (WHO) in children with CP, combined with usual multidisciplinary care, can prevent or reduce musculoskeletal impairments, including muscle stiffness/tone and loss of m..

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Awarded by ACU

Awarded by NHMRC

Funding Acknowledgements

This clinical trial is funded through a 5 year grant from ACU (#2013000413) in which CI, MW, BH, CE, SG, MR, BA, EB, DR are grant holders. Funding received from ACU will support the direct research costs and research assistant salaries. In addition, the study is embedded in a Centre for Research Excellence-Cerebral Palsy (CRE-CP), funded by the NHMRC (APP1057997), in which DR, CI and RC are chief investigators. The CRE-CP will support the studies by providing funding for a Project Coordinator, for expertise associated with conducting the economic analysis led by RC and SS and statistical support to the led by FO. A small grant was obtained from Curtin University to support development of the motion sensors, in which CE, CI, MR and BA are grant holders. The authors also acknowledge the substantial in-kind contribution made by each participating organisation in the conduct of the trial: Princess Margaret Hospital, The Ability Centre, Monash Children's Hospital, Cerebral Palsy Alliance and The Royal Children's Hospital.