Journal article

Dietary inflammatory index, Mediterranean diet score, and lung cancer: a prospective study

AM Hodge, JK Bassett, N Shivappa, JR Hebert, DR English, GG Giles, G Severi

CANCER CAUSES & CONTROL | SPRINGER | Published : 2016

Abstract

PURPOSE: To investigate prospectively the associations of Dietary Inflammatory Index (DII) and Mediterranean Diet Score (MDS) with lung cancer. METHODS: We used data from men and women aged 40-69 years at recruitment in 1990-1994, who were participants in the Melbourne Collaborative Cohort Study (n = 35,303). A total of 403 incident lung cancer cases were identified over an average 18-year follow-up. Hazard ratios (HR) were estimated using Cox regression, adjusting for smoking status and other risk factors, with age as the time metric. RESULTS: An inverse correlation was observed between the DII and MDS (ρ = -0.45), consistent with a higher DII being pro-inflammatory and less 'healthy,' whil..

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Grants

Awarded by Australian National Health and Medical Research Council


Awarded by United States National Institute for Diabetes and Digestive and Kidney Diseases


Awarded by NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES


Funding Acknowledgements

Melbourne Collaborative Cohort Study (MCCS) recruitment was funded by VicHealth and Cancer Council Victoria. The MCCS was further supported by Australian National Health and Medical Research Council Grants 209057, 251553, and 1050198 and by infrastructure provided by Cancer Council Victoria. Cases and their vital status were ascertained through the Victorian Cancer Registry (VCR) and the Australian Institute of Health and Welfare (AIHW), including the National Death Index and the Australian Cancer Database. Drs. Shivappa and Hebert were supported by Grant Number R44DK103377 from the United States National Institute for Diabetes and Digestive and Kidney Diseases.