Journal article

Rotavirus vaccination and intussusception - Science, surveillance, and safety: A review of evidence and recommendations for future research priorities in low and middle income countries

Catherine Yen, Kelly Healy, Jacqueline E Tate, Umesh D Parashar, Julie Bines, Kathleen Neuzil, Mathuram Santosham, A Duncan Steele



As of January 2016, 80 countries have introduced rotavirus vaccines into their national immunization programs. Many have documented significant declines in rotavirus-specific and all-cause diarrheal illnesses following vaccine introduction. Two globally licensed rotavirus vaccines have been associated with a low risk of intussusception in several studies. In July 2014, the Rotavirus Organization of Technical Allies Council convened a meeting of research and advocacy organizations, public health experts, funders, and vaccine manufacturers to discuss post-marketing intussusception surveillance and rotavirus vaccine impact data. Meeting objectives were to evaluate updated data, identify and pri..

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Funding Acknowledgements

We would like to thank all meeting participants, particularly the following individuals for their presentations and review of this report: Remon Abu-Elyazeed, Narendra K. Arora, Margaret E. Conner, Maria Elkin, Roger Glass, Michelle Goveia, Harry Greenberg, Jacob John, Hope Johnson, Marc Laforce, Margaret Rennels, Debora Sandiford, Molly Sauer, Mandeep Singh Dhingra, Trina Stout, Rose Weeks, Marietta Vazquez, and Melinda Wharton. Murdoch Childrens Research Institute is supported by a Victorian Government Operational Infrastructure Support Program.