Journal article

Prediction of major osteoporotic and hip fractures in Australian men using FRAX scores adjusted with trabecular bone score

KL Holloway, M Mohebbi, AG Betson, D Hans, NK Hyde, SL Brennan-Olsen, MA Kotowicz, JA Pasco

OSTEOPOROSIS INTERNATIONAL | SPRINGER LONDON LTD | Published : 2018

Abstract

There was no significant difference between the areas under receiver operating characteristics (AUROCs) and diagnostic indexes (sensitivity, specificity, positive predictive value, negative predictive value) for either major osteoporotic or hip fracture FRAX scores when comparing the unadjusted and trabecular bone score (TBS)-adjusted scores. INTRODUCTION: FRAX 10-year probability of fracture can be calculated with adjustment for the TBS. Studies have shown that TBS can improve FRAX assessments in some populations. This study aimed to determine if TBS-adjusted FRAX score is better than the unadjusted score for predicting major osteoporotic fracture (MOF) and hip fracture in Australian men. M..

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Grants

Awarded by National Health and Medical Research Council (NHMRC) of Australia


Awarded by NHMRC Career Development Fellowship


Funding Acknowledgements

The study was supported by the National Health and Medical Research Council (NHMRC) of Australia (251638, 299831, 628582), the Geelong Regional Medical Foundation, Arthritis Foundation of Australia, and Perpetual Trustees. SLB-O is supported by an NHMRC Career Development Fellowship (1107510). KLH is supported by an Alfred Deakin Postdoctoral Research Fellowship, and NKH is supported by an Australian Postgraduate Award (APA).