Journal article

Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancer

Muhammed Murtaza, Sarah-Jane Dawson, Katherine Pogrebniak, Oscar M Rueda, Elena Provenzano, John Grant, Suet-Feung Chin, Dana WY Tsui, Francesco Marass, Davina Gale, H Raza Ali, Pankti Shah, Tania Contente-Cuomo, Hossein Farahani, Karey Shumansky, Zoya Kingsbury, Sean Humphray, David Bentley, Sohrab P Shah, Matthew Wallis Show all

Nature Communications | NATURE PUBLISHING GROUP | Published : 2015


Awarded by European Research Council under the European Union's Seventh Framework Programme (FP)/ERC Grant

Awarded by Academy of Medical Sciences (AMS)

Awarded by Cancer Research UK

Awarded by Medical Research Council

Awarded by National Institute for Health Research

Awarded by National Breast Cancer Foundation

Funding Acknowledgements

We thank L. Jones, S. Richardson and H. Biggs for recruiting patients into the DETECT study, all medical and ancillary staff in the breast cancer clinic and the patient for consenting to participate. We thank the Human Research Tissue Bank at Addenbrooke's Hospital, which is supported by the NIHR Cambridge Biomedical Research Centre. We acknowledge the support of Cancer Research UK, the University of Cambridge, National Institute for Health Research Cambridge Biomedical Research Centre and Cambridge Experimental Cancer Medicine Centre. The research leading to these results has received funding from the European Research Council under the European Union's Seventh Framework Programme (FP/2007-2013)/ERC Grant Agreement no 337905. Dr Dawson was supported by an Australian National Breast Cancer Foundation and Victorian Cancer Agency Early Career Fellowship. Dr Murtaza was supported by Science Foundation Arizona's Bisgrove Scholars Early Tenure Track award.