Dietary antioxidants and chromatin modifying compounds as potential anti-cancer therapies

Abstract

Despite the efficacy of novel chemotherapeutic agents and radiation therapy, considerable developments are still necessary to improve the tolerance and reduce the toxicity in healthy cells of cancer patients. Dietary polyphenols have received increasing interest as an alternative approach, particularly in cancer treatment, as they display strong antioxidant properties and reduced toxicity profiles in normal cells. For decades, the Mediterranean diet but particularly olive oil has been linked with increased health benefits and has been associated with decreased risks in cardiovascular diseases and cancers. The minor constituents of olives are its phenolic compounds including oleuropein, tyros..