Journal article

A patient-reported outcome instrument to assess the impact of oropharyngeal mucositis on health-related quality of life: a longitudinal psychometric evaluation

Karis KF Cheng, SF Leung, Raymond HS Liang, Josepha WM Tai, Rebecca MW Yeung, David R Thompson

SUPPORTIVE CARE IN CANCER | SPRINGER | Published : 2009

Abstract

GOALS OF WORK: An oropharyngeal mucositis (OM)-specific health-related quality of life measure (OMQoL) has been developed to assess the impact of OM from the perspective of patients. The current paper describes the convergent, concurrent, and known-group validities and responsiveness in relation to clinical and health outcomes. MATERIALS AND METHODS: A multicenter approach was used, and 137 patients treated with different cancer therapies completed the OMQoL and the European Organization for Research and Treatment of Cancer Quality of Life questionnaire [EORTC QLQ-C30 (Ch)] twice over a 4-week period or weekly over a 7-week period, along with concurrent measures of OM and its related symptom..

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Funding Acknowledgements

This study was supported by a grant from the Health, Welfare and Food Bureau of Hong Kong. We thank Alta Kan, WM Ling, and Maggie Tse for their efforts in coordinating the study in different sites and the physicians and nursing staff who were involved in various aspects of this study. Our special thanks go to all patients who gave their time to this study.