Estimated GFR and the Effect of Intensive Blood Pressure Lowering after Acute Intracerebral Hemorrhage

D Zheng; S Sato; H Arima; E Heeley; C Delcourt; Y Cao; J Chalmers; CS Anderson; S Davis; Y Huang; P Lavados; B Neal; MW Parsons; R Lindley; L Morgenstern; TG Robinson; C Stapf; C Tzourio; JG Wang; S Chen; XY Chen; L Cui; Z Liu; C Lu; J Wang; S Wu; E Xu; Q Yang; C Zhang; J Zhang; R Beer; E Schmutzhard; P Redondo; M Kaste; L Soinne; T Tatlisumak; K Wartenberg; S Ricci; K Klijn; E Azevedo; A Chamorro; M Arnold; U Fischer; S Kaul; J Pandian; H Boyini; S Singh; AA Rabinstein; C Estol; G Silva; VV Olavarria; RJ Simes; MG Bousser; G Hankey; K Jamrozik; SC Johnston; S Li; K Bailey; T Cheung; S Chintapatla; E Ducasse; T Erho; J Hata; B Holder; E Knight; M Leroux; T Sassé; E Odgers; R Walsh; Z Wolfowicz; G Chen; S Fuentes; B Peng; HM Schneble; MX Wang; L Billot; S Heritier; Q Li; M Woodward; S Abimbola; S Anderson; E Chan; G Cheng; P Chmielnik; S Leighton; JY Liu; B Rasmussen; A Saxena; S Tripathy; M Armenis; MA Baig; B Naidu; G Starzec; S Steley; A Moles; A Ruiz; M Zimmermann; J Marinho; S Alves; R Angelim

Journal article

Estimated GFR and the Effect of Intensive Blood Pressure Lowering after Acute Intracerebral Hemorrhage

D Zheng, S Sato, H Arima, E Heeley, C Delcourt, Y Cao, J Chalmers, CS Anderson, S Davis, Y Huang, P Lavados, B Neal, MW Parsons, R Lindley, L Morgenstern, TG Robinson, C Stapf, C Tzourio, JG Wang, S Chen Show all

American Journal of Kidney Diseases | Published : 2016

DOI: 10.1053/j.ajkd.2016.01.020

Abstract

Background: The kidney-brain interaction has been a topic of growing interest. Past studies of the effect of kidney function on intracerebral hemorrhage (ICH) outcomes have yielded inconsistent findings. Although the second, main phase of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT2) suggests the effectiveness of early intensive blood pressure (BP) lowering in improving functional recovery after ICH, the balance of potential benefits and harms of this treatment in those with decreased kidney function remains uncertain. Study Design: Secondary analysis of INTERACT2, which randomly assigned patients with ICH with elevated systolic BP (SBP) to intensive (..

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University of Melbourne Researchers

Stephen Davis Author

Mark Parsons Author

Tissa Wijeratne Author

Bernard Yan Author

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

Dr Sato holds a fellowship from the Japan Brain Foundation. Dr Anderson reports receiving travel reimbursement and honorarium from Takeda China and Covidien.