Journal article

Gynecologic Cancer InterGroup (GCIG) Consensus Review for Ovarian and Primary Peritoneal Low-Grade Serous Carcinomas

Charlie Gourley, John Farley, Diane M Provencher, Sandro Pignata, Linda Mileshkin, Philipp Harter, Johanna Maenpaa, Jae-Weon Kim, Eric Pujaide-Lauraine, Rosalind M Glasspool, Isabelle Ray-Coquard, David Gershenson

International Journal of Gynecological Cancer | BMJ PUBLISHING GROUP | Published : 2014

Abstract

Low-grade serous ovarian cancer is a recently described histological subtype of ovarian cancer that is clinically and molecularly distinct from the 4 other main histological subtypes (high-grade serous, clear cell, endometrioid, and mucinous). In particular, it differs from high-grade serous ovarian cancer in that it presents at a much younger age, is more indolent, and is relatively chemoresistant. Very few clinical trials have been performed exclusively in this tumor type; and as such, specific data guiding optimal management are limited.

University of Melbourne Researchers