Journal article

Gynecologic cancer intergroup (GCIG) consensus review for ovarian and primary peritoneal low-grade serous carcinomas

C Gourley, J Farley, DM Provencher, S Pignata, L Mileshkin, P Harter, J Maenpaa, JW Kim, E Pujaide-Lauraine, RM Glasspool, I Ray-Coquard, D Gershenson

International Journal of Gynecological Cancer | BMJ PUBLISHING GROUP | Published : 2014

Abstract

Low-grade serous ovarian cancer is a recently described histological subtype of ovarian cancer that is clinically and molecularly distinct from the 4 other main histological subtypes (high-grade serous, clear cell, endometrioid, and mucinous). In particular, it differs from high-grade serous ovarian cancer in that it presents at a much younger age, is more indolent, and is relatively chemoresistant. Very few clinical trials have been performed exclusively in this tumor type; and as such, specific data guiding optimal management are limited.

University of Melbourne Researchers