Synthetic Lethal Screens Identify Vulnerabilities in GPCR Signaling and Cytoskeletal Organization in E-Cadherin-Deficient Cells
Bryony J Telford, Augustine Chen, Henry Beetham, James Frick, Tom P Brew, Cathryn M Gould, Andrew Single, Tanis Godwin, Kaylene J Simpson, Parry Guilford
Molecular Cancer Therapeutics | AMER ASSOC CANCER RESEARCH | Published : 2015
Awarded by New Zealand Health Research Council
This work was supported by the New Zealand Health Research Council (grant number 11/513 to P. Guilford) and the University of Otago (PhD Fellowships to B. Telford, H. Beetham, and A. Single). Additional funding support was received from No Stomach for Cancer Inc, the Degregario Family Foundation and the New Zealand Breast Cancer Research Partnership. The Victorian Centre for Functional Genomics (to K. Simpson) is funded by the Australian Cancer Research Foundation (ACRF), the Victorian Department of Industry, Innovation and Regional Development (DIIRD), the Australian Phenomics Network (APN) supported by funding from the Australian Government's Education Investment Fund through the Super Science Initiative, the Australasian Genomics Technologies Association (AMATA), the Brockhoff Foundation, and the Peter MacCallum Cancer Centre Foundation.