Journal article
Software output from semi-automated planimetry can underestimate intracerebral haemorrhage and peri-haematomal oedema volumes by up to 41 %
TY Wu, O Sobowale, R Hurford, G Sharma, S Christensen, N Yassi, T Tatlisumak, PM Desmond, BCV Campbell, SM Davis, AR Parry-Jones, A Meretoja
Neuroradiology | SPRINGER | Published : 2016
Abstract
Introduction: Haematoma and oedema size determines outcome after intracerebral haemorrhage (ICH), with each added 10 % volume increasing mortality by 5 %. We assessed the reliability of semi-automated computed tomography planimetry using Analyze and Osirix softwares. Methods: We randomly selected 100 scans from 1329 ICH patients from two centres. We used Hounsfield Unit thresholds of 5–33 for oedema and 44–100 for ICH. Three raters segmented all scans using both softwares and 20 scans repeated for intra-rater reliability and segmentation timing. Volumes reported by Analyze and Osirix were compared to volume estimates calculated using the best practice method, taking effective individual slic..
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Funding Acknowledgements
TYW is supported by grants from the Neurological Foundation of New Zealand and the Royal Melbourne Hospital Neuroscience Foundation. AP-J is supported by a National Institute for Health Research Clinician Scientist Award. The views expressed in this publication are those of the author(s) and not necessarily those of the NHS, the National Institute for Health Research or the Department of Health. AM is supported by grants from National Health and Medical Research Council (Australia), the Academy of Finland and the Finnish Medical Foundation.