Journal article

A comparison of therapeutic hypothermia and strict therapeutic normothermia after cardiac arrest

Andrew Casamento, Adrian Minson, Samuel Radford, Johan Martensson, Elliott Ridgeon, Paul Young, Rinaldo Bellomo

RESUSCITATION | ELSEVIER IRELAND LTD | Published : 2016

Abstract

BACKGROUND AND AIMS: In a recent high-quality randomised controlled trial (RCT), strict therapeutic normothermia (STN) following cardiac arrest with coma resulted in similar outcomes to therapeutic hypothermia (TH). We aimed to test the feasibility, reproducibility, and safety of the STN protocol outside of its RCT context. METHODS: In two teaching hospital ICUs, we performed a before-and-after study comparing the previously International Liaison Committee on Resuscitation (ILCOR)-endorsed TH protocol to the recently studied STN protocol. The primary feasibility end point was the percentage of temperature recordings in the prescribed range in the first 24h of treatment. Secondary end points ..

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