Design, Synthesis, and Characterization of Cyclic Peptidomimetics of the Inducible Nitric Oxide Synthase Binding Epitope That Disrupt the Protein-Protein Interaction Involving SPRY Domain-Containing Suppressor of Cytokine Signaling Box Protein (SPSB) 2 and Inducible Nitric Oxide Synthase
Jitendra R Harjani, Beow Keat Yap, Eleanor WW Leung, Andrew Lucke, Sandra E Nicholson, Martin J Scanlon, David K Chalmers, Philip E Thompson, Raymond S Norton, Jonathan B Baell
Journal of Medicinal Chemistry | AMER CHEMICAL SOC | Published : 2016
Awarded by NHMRC
Awarded by NHMRC Independent Research Institute Infrastructure Support (IRIISS)
We thank Kade Roberts for helpful discussions. B.K.Y. is the recipient of an Academic Staff Training Scheme Fellowship of Universiti Sains Malaysia. R.S.N. and J.B.B. acknowledge Fellowship support from the National Health and Medical Research Council of Australia (NHMRC). This study was supported by NHMRC research grants 1016647 and 1022693, as well as NHMRC Independent Research Institute Infrastructure Support (IRIISS) grant 361646 and a Victorian State Government Operational Infrastructure Scheme grant.