Self-Rated Depression Severity Relative to Clinician-Rated Depression Severity: Trait Stability and Potential Role in Familial Transmission of Suicidal Behavior
J John Mann, Steven P Ellis, Dianne Currier, Jamie Zelazny, Boris Birmaher, Maria A Oquendo, David J Kolko, Barbara Stanley, Nadine Melhem, Ainsley K Burke, David A Brent
Archives of Suicide Research | ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD | Published : 2016
Self-rated depression and hopelessness severity are predictors of suicide attempt in major depression. This study evaluated whether: (1) greater self-rated distress relative to severity of clinician-rated depression is a trait; (2) that trait is familial; and (3) that trait is linked to familial transmission of suicidal behavior. A total of 285 mood disorder probands and 457 offspring were assessed twice, at least 1 year apart. Family and subject intra-class correlations for self-report depression and hopelessness, controlling for clinician-rated depression severity, were computed. Mixed general linear models determined offspring-proband correlations. Within-individual intra-class correlatio..View full abstract
This work was supported by MH56390, MH48514, and MH62185.