Journal article

LDL RECEPTOR-RELATED PROTEIN, A MULTIFUNCTIONAL APOE RECEPTOR, BINDS SECRETED BETA-AMYLOID PRECURSOR PROTEIN AND MEDIATES ITS DEGRADATION

MZ KOUNNAS, RD MOIR, GW REBECK, AI BUSH, WS ARGRAVES, RE TANZI, BT HYMAN, DK STRICKLAND

Cell | CELL PRESS | Published : 1995

DOI: 10.1016/0092-8674(95)90320-8

Grants

Awarded by NHLBI NIH HHS

Awarded by NIDDK NIH HHS

Awarded by NIGMS NIH HHS

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Keywords

Receptors, Lipoprotein
Cell
Purification
Humans
Plasminogen-Activator
Alpha-2-Macroglobulin Receptor
Life Sciences & Biomedicine
Low Density Lipoprotein Receptor-Related Protein-1
Antibodies, Monoclonal
Density-Lipoprotein Receptor
Nexin-Ii
Aprotinin
Enzyme-Linked Immunosorbent Assay
Receptors, Immunologic
Science & Technology
Cricetinae
Kinetics
Cho Cells
Endocytosis
Animals
Transfection
Amyloid Beta-Protein Precursor
Cell Biology
Fibroblasts
Recombinant Proteins
Protein Binding
Sporadic Alzheimers-Disease
Apolipoprotein-E
Mice
Activator Inhibitor Type-1
Cells, Cultured
Messenger-Rna
Biochemistry & Molecular Biology
Binding Sites