Journal article

Zinc-induced Alzheimer's A beta 1-40 aggregation is mediated by conformational factors

XD Huang, CS Atwood, RD Moir, MA Hartshorn, JP Vonsattel, RE Tanzi, AI Bush

Journal of Biological Chemistry | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 1997

DOI: 10.1074/jbc.272.42.26464

Grants

Awarded by NIA NIH HHS

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Keywords

Neurotoxicity
Protein-Precursor
Humans
Deposition
Science & Technology
Peptide Fragments
Cleavage
Platelets
Alzheimer Disease
Fragments
Chromatography, Gel
Life Sciences & Biomedicine
Amyloid Beta-Peptides
Cortical-Neurons
Disease Brains
Brain
Protein Conformation
Beta-Amyloid Peptides
Zinc
Protein Binding
Biochemistry & Molecular Biology
Pathogenesis